Ikuro Maruyama Selected Research

HMGB1 Protein (HMG1)

1/2021	Specific detection of high mobility group box 1 degradation product with a novel ELISA.
1/2021	Differential Regulation of Damage-Associated Molecular Pattern Release in a Mouse Model of Skeletal Muscle Ischemia/Reperfusion Injury.
7/2020	Association Between HMGB1 and Thrombogenesis in a Hyperlipaemia-induced Microminipig Model of Atherosclerosis.
1/2018	HMGB proteins and arthritis.
11/2016	HMGB1 Promotes Intraoral Palatal Wound Healing through RAGE-Dependent Mechanisms.
1/2016	HMGB1 is secreted by 3T3-L1 adipocytes through JNK signaling and the secretion is partially inhibited by adiponectin.
4/2015	Gene transfer of high-mobility group box 1 box-A domain in a rat acute liver failure model.
1/2014	Overexpression of receptor for advanced glycation end products and high-mobility group box 1 in human dental pulp inflammation.
1/2014	HMGB1 promotes the development of pulmonary arterial hypertension in rats.
9/2013	Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ikuro Maruyama Research Topics

Disease

33	Inflammation (Inflammations) 01/2021 - 12/2004
21	Sepsis (Septicemia) 01/2021 - 12/2004
16	Disseminated Intravascular Coagulation 02/2022 - 12/2003
15	Thrombosis (Thrombus) 03/2021 - 01/2010
14	Neoplasms (Cancer) 01/2022 - 11/2002
11	Atherosclerosis 07/2020 - 04/2002
10	Ischemia 01/2021 - 12/2003
8	Septic Shock (Toxic Shock Syndrome) 01/2016 - 05/2003
7	Reperfusion Injury 01/2019 - 01/2005
7	Wounds and Injuries (Trauma) 01/2019 - 11/2005
6	Melanoma (Melanoma, Malignant) 10/2020 - 07/2008
6	Stroke (Strokes) 10/2018 - 12/2010
6	Rheumatoid Arthritis 01/2018 - 04/2003
6	Acute Lung Injury 03/2013 - 12/2004
5	Infarction (Infarctions) 09/2021 - 06/2009
5	Hemorrhage 10/2020 - 05/2005
5	Cerebral Infarction 01/2012 - 06/2009
4	Hypoxia (Hypoxemia) 09/2021 - 01/2004
4	Thrombocytopenia (Thrombopenia) 01/2021 - 04/2011
4	Infections 10/2020 - 04/2011
4	Cardiovascular Diseases (Cardiovascular Disease) 08/2017 - 12/2005
4	Hypertension (High Blood Pressure) 09/2013 - 04/2002
4	Shock 11/2012 - 05/2003
4	Lung Injury 05/2010 - 08/2008
4	Hepatocellular Carcinoma (Hepatoma) 01/2006 - 11/2003
3	Multiple Organ Failure (MODS) 01/2021 - 09/2013
3	Communicable Diseases (Infectious Diseases) 01/2019 - 11/2005
3	Brain Ischemia (Cerebral Ischemia) 10/2018 - 10/2009
3	Ischemic Stroke 01/2017 - 12/2009
3	Obesity 01/2016 - 11/2005
3	Periodontitis 01/2015 - 05/2005
3	Endotoxemia 11/2011 - 07/2008
3	Joint Diseases (Joint Disease) 09/2008 - 10/2003
3	Myocardial Infarction 12/2004 - 03/2003
2	Lung Neoplasms (Lung Cancer) 01/2022 - 06/2009
2	Hematologic Neoplasms (Hematological Malignancy) 10/2020 - 04/2011
2	Diabetes Complications 01/2019 - 07/2012
2	Osteoarthritis 01/2018 - 09/2008
2	Arthritis (Polyarthritis) 01/2018 - 09/2008
2	Thromboembolism 10/2016 - 01/2013
2	Body Weight (Weight, Body) 04/2015 - 09/2013
2	Acute Liver Failure (Fulminant Hepatic Failure) 04/2015 - 12/2010

Drug/Important Bio-Agent (IBA)

44	HMGB1 Protein (HMG1)IBA 01/2021 - 12/2004
28	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
14	Dacarbazine (DIC)FDA LinkGeneric 02/2022 - 12/2003
14	CytokinesIBA 03/2013 - 04/2003
12	ThrombomodulinIBA 02/2022 - 09/2004
11	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2011 - 05/2002
10	Histones (Histone)IBA 01/2021 - 11/2008
9	AnticoagulantsIBA 10/2020 - 09/2004
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2010 - 12/2007
6	EdaravoneIBA 01/2017 - 06/2009
6	Thrombin FDA Link 01/2016 - 05/2002
6	EndotoxinsIBA 03/2012 - 05/2005
5	EnzymesIBA 01/2019 - 10/2003
5	Thromboplastin (Tissue Factor)IBA 10/2016 - 03/2003
5	Receptor for Advanced Glycation End ProductsIBA 01/2014 - 11/2005
5	Interleukin-6 (Interleukin 6)IBA 03/2013 - 05/2005
5	LipopolysaccharidesIBA 11/2011 - 05/2005
5	anandamide (arachidonylethanolamide)IBA 01/2006 - 05/2003
4	FibrinIBA 03/2021 - 12/2004
4	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2018 - 03/2003
4	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 08/2013 - 10/2009
4	Superoxides (Superoxide)IBA 09/2010 - 10/2009
4	CannabinoidsIBA 05/2008 - 05/2003
3	AsparagineIBA 01/2022 - 01/2019
3	Heparin (Liquaemin)FDA LinkGeneric 10/2020 - 11/2010
3	ImmunosorbentsIBA 01/2019 - 07/2008
3	HMGB ProteinsIBA 01/2018 - 12/2004
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2015 - 10/2003
3	AntigensIBA 01/2015 - 06/2004
3	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2014 - 05/2005
3	Protein CIBA 01/2013 - 09/2009
3	LipidsIBA 09/2012 - 11/2003
3	salicylhydroxamic acid (SHAM)IBA 09/2012 - 10/2009
3	Messenger RNA (mRNA)IBA 06/2012 - 05/2002
3	C-Reactive ProteinIBA 04/2012 - 12/2004
3	Intravenous Immunoglobulins (IVIG)FDA Link 03/2012 - 04/2009
3	Free Radical ScavengersIBA 09/2011 - 06/2009
3	Pharmaceutical PreparationsIBA 12/2010 - 04/2006
3	Malondialdehyde (Propanedial)IBA 09/2010 - 10/2009
3	NF-kappa B (NF-kB)IBA 01/2006 - 05/2005
2	LectinsIBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2008
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2021 - 11/2008
2	Syndecan-1 (Syndecan 1)IBA 01/2021 - 02/2018
2	Hemostatics (Antihemorrhagics)IBA 10/2020 - 10/2020
2	Matrix Metalloproteinases (MMPs)IBA 07/2020 - 09/2011
2	ChromatinIBA 01/2019 - 01/2013
2	SolutionsIBA 01/2019 - 01/2010
2	Polysaccharides (Glycans)IBA 01/2019 - 01/2019
2	HMGB2 ProteinIBA 01/2018 - 12/2004
2	CollagenIBA 10/2016 - 01/2014

Therapy/Procedure

17	Therapeutics 10/2020 - 11/2002
8	Blood Component Removal (Apheresis) 06/2006 - 08/2002
5	Ligation 01/2021 - 09/2006
4	Punctures 01/2018 - 09/2006
3	Renal Dialysis (Hemodialysis) 08/2017 - 12/2003
3	Hemoperfusion 03/2010 - 01/2007
2	Critical Care (Surgical Intensive Care) 01/2021 - 01/2019